The 51-year-old was tested when he arrived at Madrid airport on Sunday via Amsterdam and was found to be positive, the regional government of Madrid said in a statement.
“The patient has light symptoms and is undergoing quarantine,” the statement added.
Earlier on Monday, Madrid’s Gregorio Maranon Hospital tweeted that its microbiology service had detected the first case of the Omicron variant in Spain, without giving further details.
The World Health Organization has listed Omicron as a “variant of concern” and countries around the world are now restricting travel from southern Africa, where the new strain was first detected, and taking other new precautions.
The WHO says it could take several weeks to know if there are significant changes in transmissibility, severity or implications for Covid vaccines, tests and treatments.
Several other European nations, including Belgium, Britain and Germany have detected cases of the variant, which was first detected in South Africa.
On Friday, Spanish authorities suspended flights with South Africa and Botswana in reaction to growing concerns over the new variant which was first detected in the South African city of Pretoria.
The following day, Spain’s Health Ministry put Botswana, Eswatini, Lesotho, Mozambique, Namibia, South Africa and Zimbabwe on its new high-risk list.
Travellers who are able to reach Spain from these nations will have to present a negative PCR or NAAT test taken within 72 hours prior to travel to Spain even if they are fully vaccinated.
They must also go into quarantine for 10 days upon arrival in Spain, or for their whole stay if it’s under 10 days.