Only legal residents or nationals of Spain and the neighbouring micro-state of Andorra are currently allowed in on flights from these countries.
The only exceptions are for passengers in transit who cannot leave the airport nor remain there longer than 24 hours.
The restrictions took effect on February 2 and have been repeatedly extended.
Other European nations have imposed similar curbs due to fears that new variants may spread more easily or contain mutations that allow the virus to evade the effects of vaccines.
Since February 22nd, all passengers arriving in Spain from Brazil or South Africa have been obliged to undergo 10 days of compulsory quarantine, or seven if they can show a negative test.
On March 8, that requirement was extended to arrivals from another 10 countries, including Colombia and Peru, where there is community transmission of the Brazilian strain.
Spain has been hit hard by the pandemic, recording over 77,000 deaths from more than 3.4 million cases.