Spanish prosecutors want to charge Puigdemont, with rebellion, sedition and misuse of public funds over his role in the region's tumultuous independence drive. The 54-year-old has ignored a summons to appear in Madrid.
The former journalist had called for a plebiscite since he became president of Catalonia in January 2016, after an election in which separatists won a majority in the regional parliament for the first time.
His staging of a Catalan independence referendum on October 1, despite a court ban, has triggered Spain's worst political crisis in decades. Spanish police tried and failed to stop it, in some cases firing rubber bullets.
An independence declaration by the Catalan parliament followed one week ago. Spain's government responded by dismissing Puigdemont's government, imposing direct rule and calling fresh elections in Catalonia on December 21.
"I was elected. What is the purpose of (new) elections?" Puigdemont said, accusing Spanish Prime Minister Mariano Rajoy of "illegally" dissolving the Catalan parliament.
A virtual unknown when became president of the northeastern Spanish region of 7.5 million people, Puigdemont, who combs his hair in a shaggy Beatles-style mop, has become the main enemy of Prime Minister Mariano Rajoy's conservative government.
"In order to resolve political problems you need to play politics. You don't imprison those who think differently to you," Puigdemont said, while adding that he was prepared to run as a candidate in the upcoming polls.
Always a separatist
In Amer, the small mountainous village of 2,200 people where he grew up, and in Girona, where Puigdemont served as mayor from 2011 to 2016, he is recalled as a convinced separatist.
"In Catalonia many people became separatists in an allergic reaction to Madrid's policies. Not him, he always had these convictions," said Puigdemont's friend Antoni Puigverd, a poet and journalist.
Puigdemont has never hidden his separatist tendencies, not even when he joined his predecessor Artur Mas's CDC party in 1980 at a time when it merely wanted to negotiate greater autonomy for Catalonia -- far from the idea of breaking away from Spain.
His friend Salvador Clara, a leftwing secessionist councillor in Amer, added that Puigdemont had defended the independence of Catalonia "since he can remember".
In July 2015 Puigdemont became president of the Association of Municipalities for Independence, which brings together local entities to promote the right to self-determination.
For 17 years he worked for Catalonia's nationalist daily El Punt, which now publishes under the name El Punt Avui after merging with another paper. He later created a regional news agency and an English-language newspaper about his region.
"He always combined his political activism with journalism," said Ramon Iglesias, a journalist with news radio Cadena Ser in Girona.
In 1991, while working at a local newspaper in Girona, Puigdemont launched a campaign to change the spelling of the name of the city from the Spanish version, Gerona, to Girona, the Catalan spelling, Iglesias recalled.
For Silvia Paneque, head of the opposition Socialists in Girona, Puigdemont at times carries out a form of nationalism that "insists in separating those for and against independence."
He was born on December 29, 1962, into a family of bakers -- the second of eight siblings.
"We're a pro-independence family through and through," his sister Anna, who runs the family bakery in Amer, told AFP.
Puigdemont speaks English and French as did his predecessor Artur Mas, as well as Romanian -- his wife Marcela Topor comes from Romania, and they have two girls.
But unlike Mas, who implemented unpopular austerity measures during Spain's economic crisis, Puigdemont is more of a social democrat who was better able to seduce the far-left members of Catalonia's separatist faction who were wary of Mas.
Catalan journalist Enric Juliana said Puigdemont's long-standing separatist convictions made him the "ideal candidate" to succeed Mas, who never managed to convince some separatists of his dedication to a cause he embraced only a few years ago.
"He arrived where he is by chance. He did not aspire to a political career, and that has given him enormous freedom," Puigverd said.
By AFP's Daniel Bosque