Many of the Tweets poked fun at the intensity - or lack of - of the earthquake.
"I survived the Madrid earthquake 2015"
This was about the extent of the damage in Madrid.
First dramatic shot of the earthquake aftermath.
A show of solidarity with the town at the epicentre of the earthquake, Albacete.
Cuando hay terremoto en España. pic.twitter.com/wiP2E6w1kq— Universo Simpson (@UniversoSimpson) February 23, 2015
Many Tweeters chose The Simpsons to illustrate their feelings about the earthquake.
"I'm going in Ned Flanders' bunker"
And of course, the earthquake was the perfect opportunity to poke fun at politicians. Ana Botella, Madrid's mayor, famously said "there is nothing quite like a relaxing cup of café con leche in Plaza Mayor" during Madrid's bid to host the Olympic games. The phrase was turned on its head on Twitter after Monday's earthquake.
Terremoto en Madrid 2015: NEVER FORGET pic.twitter.com/S3j4n3ePjX— Proscojoncio (@Proscojoncio) February 23, 2015