"The paper edition has been closed" since Friday, said a spokeswoman for the strongly conservative newspaper, which was founded in 1989 and employs about 60 people.
"The newspaper will continue, but online — that is what we will focus on," the spokeswoman told news agency AFP.
She was unable to say what the impact would be on jobs.
La Gaceta launched as an economic paper in 1989 before converting to general news, part of the Intereconomia media group that also runs a television channel and a radio station.
The paper in 2013 tried to increase its print readership with controversial covers including one of a picture of a nude 83-year-old bullfighter showing off his scars.
It is a high-profile casualty of a finance crisis that has shut down hundreds of Spanish media organisations over the past five years, during which Spain has gone through two recessions.
In November, authorities in Valencia shut down the indebted regional broadcaster RTVV, which employed 1,700 people.
The Madrid Press Association, a journalists' body, says 284 media organisations have disappeared and 11,151 jobs been lost in the sector since 2008. That includes 73 media organisations and 4,434 jobs in 2013 alone.
The Federation of Journalists' Associations of Spain estimates the job losses at 10,500 since 2009.